During gel electrophoresis migration of DNA fragments leading to their separation takes place on the agarose gel. Choose the correct option: A). The smaller the fragment size, the farther it moves. B). Positively charged fragments moves to farther end. C). The larger the fragment size, the farther it moves. D). The negatively charged fragments do not move.

The correct answer is The smaller the fragment size, the farther it moves.. **SOLUTION** In gel electrophoresis, the agarose matrix acts as a sieve. Because DNA is negatively charged, all fragments move toward the positive anode. However, the matrix impedes larger molecules more than smaller ones. Therefore, **the smaller the fragment size, the farther (and faster) it moves** down the gel.

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During gel electrophoresis migration of DNA fragments leading to their separation takes place on the agarose gel. Choose the correct option:

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