CBSE 2025, Set 1

Question

The sequence of nitrogenous bases in a segment of a coding strand of DNA is $5^{\prime}	ext{-AATGCTAGGCAC-}3^{\prime}$. Choose the option that shows the correct sequence of nitrogenous bases in the mRNA transcribed by the DNA. A). $5^{\prime}	ext{-UUACGAACCGAG-}3^{\prime}$ B). $5^{\prime}	ext{-AAUGCUAGGCAC-}3^{\prime}$ C). $5^{\prime}	ext{-UUACGUACCGUG-}3^{\prime}$ D). $5^{\prime}	ext{-AACGUAGGCAGC-}3^{\prime}$

Edvaya · Accepted Answer

The correct answer is $5^{\prime}	ext{-AAUGCUAGGCAC-}3^{\prime}$. **SOLUTION** The primary transcript (mRNA) is synthesized complementary to the *template* strand of the DNA. Therefore, the sequence of the mRNA is exactly identical to the sequence of the **coding strand** of the DNA, with the sole exception that Thymine (T) is replaced by Uracil (U). Given coding strand: $5^{\prime}	ext{-AATGCTAGGCAC-}3^{\prime}$ Resulting mRNA: $5^{\prime}	ext{-AAUGCUAGGCAC-}3^{\prime}$

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Biology > Reproduction And Genetics > Molecular Basis Of Inheritance

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